Himalaya SEPTILIN, Herbal Supplement -100 Tablets (2 Pack)

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Septilin is an ayurvedic herbomineral formulation which has a number of beneficial health effects. It consists of six different medicinal plant extracts. These plants in their individual capacities also have medicinal properties. In view of this, septilin was selected to study its protective effects against CP induced genotoxicity. In the present study, it demonstrated effective chemoprotective properties against the CP induced clastogenecity in in vivo mouse and it did not induce any cytotoxic effects. The results revealed the anticlastogenic and genoprotective effects of septilin. Even if you are on antibiotics, add septilin to treatment, you will notice excellent results. Septilin Indications and my experience. This could be a blessing for those who suffer from frequent respiratory infections in winter due to dust pollution.

Septilin has soothing action and anti-inflammatory properties due to which it is effective remedy for sore throat. In mild cases, it can work alone, but in severe cases, it should be given with Gandhak Rasayan and Yashad Bhasma (calcined zinc). Bronchitis Boosts digestion: Septilin Tablet contains herbs that help improve digestion and relieve symptoms such as bloating, gas, and constipation. Please consult your physician before using this product, especially if you have any underlying medical conditions or are taking any medications.

Cyclophosphamide (CP) is widely used anticancer and chemotherapeutic drug [90]. However, despite its wide spectrum of clinical benefits it can also induce cytotoxic effects on the normal cells in humans and experimental animals [44]. CP is an alkylating agent capable of inducing gene mutations, chromosomal aberrations, micronucleus (MN), sister chromatid exchanges, as well as other genotoxic effects [51], [1]. Since CP is a well-known mutagen/genotoxin, in the present study it was used as a positive mutagen. There are several reports on the use of CP to evaluate the anticlastogenic/antigenotoxic effects of various natural compounds and other chemicals [87], [61], [28], [92], [32], [33], [18], [70]. [42] reported the anticlastogenic effect of Ricinus communis extract against CP induced clastogenicity in mice bone marrow cells. Tinospora Gulancha (Guduchi) is a potent antimicrobial that has immunomodulatory properties, which helps in increasing the level of antibodies. This helps in building up the body’s resistance to infections.

Huynh NC-N, et al. (2016). Rinsing with saline promoteshuman gingival fibroblast wound healing in vitro. DOI:

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Moghaddam, A. A., et al. (2017). Clinical evaluation of effects of local application of aloe vera gel as an adjunct to scaling and root planning in patients with chronic periodontitis.

A 2017 review concludes that regular oil-pulling combined with a good oral hygiene routine helps reduce levels of bacteria in the mouth. 2. Herbal extracts Tripathi et al. [101], Damle [16] and Devprakash et al. [19] reviewed the phytochemical and pharmacological profile of Tinospora cordifolia (TCE). Sharma et al. [88] reported the radiation induced testicular injury and its amelioration by Tinospora cordifolia extract. Pretreatment with TCE protected the testicular cells from radiation damage. The effect is attributed to various factors especially efficient free radical scavenging. In the present study, septilin showed the protective effects against CP induced chromosomal damage. Probably the mechanism of action may be similar to the radiation protection events. Tinospora cordifolia also showed protective action against radiation induced biochemical alterations in liver. Irradiation of mice resulted in the elevation of biochemical parameters whereas; pretreatment with Tinospora cordifolia restored such alteration compared with radiation alone treated group [85]. Pretreatment with the extract of Tinospora cordifolia ameliorated the irradiation induced histopathological changes in mice ovarian tissue showing its protective effect against gamma radiation induced tissue damage [84]. Cat timp ii pot da Septilin si daca pot sa ii mai dau si alt medicament homeopat in completare .Mentionez ca nu am facut pauza la administrare In recent years much attention is being given for the discovery of cell/genoprotective agents from the natural sources against the damaging effects of chemicals and radiations. Numerous studies have been carried out in the last four decades to identify the compounds that might protect the humans against the DNA damage and its consequences. In this line, more emphasis has been given to the medicinal plants and their isolated bioactive components. Septilin, is one of the ayurvedic herbo mineral [46] preparation of the Himalayan Drug Company containing extracts of six different plants and powders of Blasmodendron mukul and shankha bhasma. There are reports on the antibacterial, antiinflammatory, immunomodulatory and immunopotentiating effects of septilin and it is extensively used for the treatment of several acute and chronic infections [62], [45]. CP is a well-known anticancer, chemotherapeutic and immunosuppressive drug, which was used as a clastogenic agent in the present study. The results obtained in this study revealed the protective effects of the septilin against the genotoxicity of CP in mouse. Administration of CP alone induced significant micronuclei in both bone marrow and peripheral blood cells and also it reduced the P/N ratio in bone marrow cells. Although CP has potent therapeutic value it also shows wide spectrum of cytotoxicity against normal cells which is a hindrance for its usage. The cytotoxicity of drug is mainly due to its ability to damage DNA. CP is an alkylating agent and its alkyl group can bond with nucleic acids resulting in DNA strand breaks, micronuclei formation and ultimately by the cell death [37]. CP showed significant effects in all the parameters used. In the combined treatment groups, septilin significantly reduced MN induced by CP and it enhanced the P/N ratio significantly. In the peripheral blood also CP significantly reduced the mean percent of PCE, and also it reduced the frequency of MN in NCE induced by CP.A 2019 meta-analysis found that taking antioxidants may help to reduce gum inflammation associated with gum disease. Specifically, it may lead to the following oral health improvements: Guduchi (Tinospora Gulancha) is a potent antimicrobial that has immunostimulatory properties, which helps in increasing the level of antibodies. This helps in building up the body’s resistance to infections. Tripathi, P., et al. (2019). Antioxidant therapy (lycopene and green tea extract) in periodontal disease: A promising paradigm. Answer: Septilin tablets are generally well-tolerated. However, in rare cases, it may cause mild gastrointestinal discomfort. If you experience any unusual side effects, please consult your physician.