HAZET 2250-3 31 mm Adapter - Chrome-Plated

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Borzova VA, Markossian KA, Chebotareva NA, Kleymenov SY, Poliansky NB, Muranov KO, Stein-Margolina VA, Shubin VV, Markov DI, Kurganov BI (2016) Kinetics of thermal denaturation and aggregation of bovine serum albumin. PLoS One 11:e0153495 Liu Y., Shen Y., Zhang W. N., Weng J. N., Zhao M. T., Zhu T. S., Chi Y. R., Yang Y. H., Zhang H., Huo F. W., Chem. Commun., 2019, 55, 11770 IBM System/360 Component Description IBM 2250 Display Unit Model 2 IBM 2840 Display Control Model 1 GA27-2702-0. The selective GAPDH inhibitors koningic acid 9 and DMF 18, 31 displayed cytotoxicity in a multitude of cancer cell lines in vitro and in vivo, including colon cancer cells, 32 breast cancer cells, 33 melanoma cells 34 and hepatocellular carcinoma. 35 Zhang W. N., Lu G., Cui C. L., Liu Y. Y., Li S. Z., Yan W. J., Xing C., Chi Y. R., Yang Y. H., Huo F. W., Adv. Mater., 2014, 26, 4056

We compared patients on MV who were treated at least once in ICUs (ICU group) and those who never stayed in ICUs (non-ICU group). Patients whose treatment was started in non-ICU settings and who were then transferred to ICUs were counted in the ICU group, regardless of whether they started MV before or after ICU admission. “MV” includes both intubated MV and acute-phase non-invasive MV with partial arterial pressure of oxygen (PaO 2) < 300 mmHg or partial arterial pressure of carbon dioxide (PaCO 2) > 45 mmHg. “ICU” was defined here as “officially certified ICU” in accordance with Japanese government insurance policy. The criteria for an officially certified ICU include staffing of the unit with at least one physician in-house 24 hourly and with nurses at a ratio of one nurse to two patients; in addition, a certified ICU must be fully equipped with hardware to resuscitate critically ill patients. In Japan there are many quasi-ICU units that treat severely ill patients and function similar to ICUs but not officially certified. These quasi-ICUs were counted among non-ICUs. Quartin AA, Campos MA, Maldonado DA, et al. Acute lung injury outside of the ICU: incidence in respiratory isolation on a general ward. Chest. 2009;135(2):261–8. What is 2250 Divided by 3 Using Long Division?". VisualFractions.com, http://visualfractions.com/calculator/long-division/what-is-2250-divided-by-3-using-long-division/. Accessed 28 November, 2023. Ferguson ND, Frutos-Vivar F, Esteban A, et al. Clinical risk conditions for acute lung injury in the intensive care unit and hospital ward: a prospective observational study. Crit Care. 2007;11(5):R96. He L. C., Liu Y., Liu J. Z., Xiong Y. S., Zheng J. Z., Liu Y. L., Tang Z. Y., Angew. Chem. Int. Ed., 2013, 52, 3741Zhang Z. J., Zhang S. L., Yao Q. L., Feng G., Zhu M. H., Lu Z. H., Inorg. Chem. Front., 2018, 5, 370

Umegaki T, Sekimoto M, Hayashida K, et al. An outcome prediction model for adult intensive care. Crit Care Resusc. 2010;12:96–103. Magde D, Rojas GE, Seybold PG (1999) Solvent dependence of the fluorescence lifetimes of xanthene dyes. Photochem Photobiol 70:737–744 Hersch M, Sonnen M, Karlic A, et al. Mechanical ventilation of patients hospitalized in medical wards vs the intensive care unit – an observational, comparative study. J Crit Care. 2007;22:13–7. Weerasinghe AJ, Schmiesing C, Varaganti S, Ramakrishna G, Sinn E (2010) Single- and multiphoton turn-on fluorescent Fe3+ sensors based on Bis(rhodamine). J Phys Chem B 114:9413–9419

Kim S, Ohulchanskyy TY, Pudavar HE, Pandey RK, Prasad PN (2007) Organically modified silica nanoparticles co-encapsulating photosensitizing drug and aggregation-enhanced two-photon absorbing fluorescent dye aggregates for two-photon photodynamic therapy. J Am Chem Soc 129:2669–2675 Fan Z. Y., Staiger L., Hemmer K., Wang Z., Wang W. J., Xie Q. J., Zhang L. J., Urstoeger A., Schuster M., Lercher J. A., Cokoja M., Fischer R. A., Cell Rep. Phys. Sci., 2022, 3, 100757 Hawe A, Sutter M, Jiskoot W (2008) Extrinsic fluorescent dyes as tools for protein characterization. Pharm Res 25:1487–1499 Zhang W. L., Shi W. X., Ji W. L., Wu H. B., Gu Z. D., Wang P., Li X. H., Qin P. S., Zhang J., Fan Y., Wu T. Y., Fu Y., Zhang W. N., Huo F. W., ACS Catal., 2020, 10, 5805

Inhibition of glycolytic and TCA cycle‐related enzymes. (A) Recombinant human GAPDH treated with 100 and 250μM GP‐2250 for 30 and 60min, followed by GAPDH enzyme activity assay. (B) Inhibition of GAPDH activity in Panc Tul and BxPC3 cells following incubation with GP‐2250 (500μM) for 24h. The GAPDH inhibitor DMF, 100μM, was included as control. (C) Human recombinant hexokinase 2 (HK2) incubated with 250 and 500μM GP‐2250 for 60min. Formation of NADH was measured every 5min. (D) Inhibition of hexokinase 2 (HK2)activity in Panc Tul and BxPC3 cells following incubation with GP‐2250 (250, 500 and 1000μM) for 24h. (E) Inhibition of alpha‐ketoglutarate dehydrogenase (αKGDH) following treatment of Panc Tul and BxPC3 cells for 24h with GP‐2250 (250, 500 and 1000μM). (F) Inhibition of pyruvate dehydrogenase (PDH) following treatment of Panc Tul and BxPC3 cells for 24h with GP‐2250 (250 and 500μM). Concentrations of GP‐2250 ranging from 100 to 1000μM were used in the cellular assays of GAPDH, HK2, αKGDH and PDH, Shown are the results of the lowest effective concentrations, respectively. * p≤0.05, significant; ** p≤0.01, highly significant; *** p≤0.001, extremely significant. DMF, dimethylfumarate; GAPDH, glyceraldehyde‐3‐phosphate‐dehydrogenase; HK2, hexokinase 2; NADH, nicotinamide adenine dinucleotide+hydrogen; NC, negative control; U, untreated.Model 2 – attached via a 2840-1 control unit. A 2840 could attach up to four 2250s and provided buffering and a character generator. An optional character-generator feature on all models provided predefined fonts of 63 characters to simplify display of alphanumeric information. Guo J., Qin Y. T., Zhu Y. F., Zhang X. F., Long C., Zhao M. T., Tang Z. Y., Chem. Soc. Rev., 2021, 50, 5366 Duke GJ, Barker A, Rasekaba T, et al. Development and validation of the critical care outcome prediction equation, version 4. Crit Care Resusc. 2013;15:191–7.

Zhang W. L., Ji W. L., Li L. J., Qin P. S., Khalil I. E., Gu Z. D., Wang P., Li H. F., Fan Y., Ren Z., Shen Y., Zhang W. N., Fu Y., Huo F. W., ACS Appl. Mater. Interfaces, 2020, 12, 52660 Lu G., Li S. Z., Guo Z., Farha O. K., Hauser B. G., Qi X. Y., Wang Y., Wang X., Han S. Y., Liu X. G., DuChene J. S., Zhang H., Zhang Q. C., Chen X. D., Ma J., Loo S. C. J., Wei W. D., Yang Y. H., Hupp J. T., Huo F., Nat. Chem., 2012, 4, 310 Behrendt CE. Acute respiratory failure in the United States: incidence and 31-day survival. Chest. 2000;118(4):1100–5. The 2250 was housed in a desk with an alphanumeric ( QWERTY) keyboard and a separate programmed function keyboard which had keys, indicator lights and switches. A plastic overlay label could be placed over the function keyboard. Punches on the top edge of the overlay could be sensed by the computer so the keys, lights and switches could be reprogrammed simply by changing overlays. The 2250s CRT measured 21" diagonal, but the useful display area was 12inch by 12inch. A light pen was provided as a pointing device, serving the function of the modern computer mouse.Zhao M. T., Yuan K., Wang Y., Li G. D., Guo J., Gu L., Hu W. P., Zhao H. J., Tang Z. Y., Nature, 2016, 539, 76 He H. H., Li L. Y., Liu Y., Kassymova M., Li D. D., Zhang L. L., Jiang H. L., Nano Res., 2021, 14, 444 Kemnitz K, Yoshihara K (1991) Entropy-driven dimerization of xanthene dyes in nonpolar solution and temperature-dependent fluorescence decay of dimers. J Phys Chem 95:6095–6104 Moriyama Y, Watanabe E, Kobayashi K, Harano H, Inui E, Takeda K (2008) Secondary structural change of bovine serum albumin in thermal denaturation up to 130 °C and protective effect of sodium dodecyl sulfate on the change. J Phys Chem B 112:16585–16589