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SANPROBI IBS, CAPSULES results in a reduction of abdominal pain, bloating, and normalization of bowel movements 20 PCS.

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The number of studies on this topic increases and data are mounting that metformin treatment is associated with changes in gut bacterial composition. Huang WC, Lee MC, Lee CC, Ng KS, Hsu YJ, Tsai TY, Young SL, Lin JS, Huang CC. Effect of Lactobacillus plantarum TWK10 on Exercise Physiological Adaptation, Performance, and Body Composition in Healthy Humans. Nutrients. 2019 Nov 19;11(11):2836. doi: 10.3390/nu11112836.

Szulinska M, Loniewski I, van Hemert S, Sobieska M, Bogdanski P. Dose-Dependent Effects of Multispecies Probiotic Supplementation on the Lipopolysaccharide (LPS) Level and Cardiometabolic Profile in Obese Postmenopausal Women: A 12-Week Randomized Clinical Trial. Nutrients. 2018 Jun 15;10(6):773. doi: 10.3390/nu10060773.The energy value of the daily nutritional plan, the content of the main nutrients, vitamins, minerals, cholesterol and dietary fiber were taken into account in the evaluation of the three-day nutrition diary.

kapsułka zawiera 1×10 10 CFU/g całkowitej liczba bakterii probiotycznych Lactobacillus paracasei 8700:2, Lactobacillus plantarum HEAL 9 i Lactobacillus plantarum HEAL 19 oraz 1,5 µg witaminy D3; kapsułka zawiera łącznie 1×10 9 CFU/g bakterii Lactococcus lactis spp. lactis Rossel – 1058, Lactobacillus casei Rosell – 215, Lactobacillus helveticus Rosell – 52 i Bifidobacterium bifidum Rosell – 71

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None of the competitors had an implanted pacemaker, which is an absolute exclusion criterion in the study of body composition analysis by electrical bioimpedance.

Patients who will be randomized to probiotic/ placebo "B" at visit 2 will be switched to probiotic/ placebo "A" at visit 6 and patients who will be randomized to group probiotic/ placebo "A" at visit 2 will be switched to probiotic/ placebo "B" at visit 6. Wskazanie to parametr, który określa w jakim celu dany lek bądź suplement diety może być stosowany. Może to być np. uzupełnienie diety w składniki odżywcze, wsparcie organizmu w stanach niedoboru, poprawa zdrowia i samopoczucia. Wskazanie produktu jest ważne, ponieważ pozwala dobrać lek bądź suplement diety do indywidualnych potrzeb Użytkownika.Fasting state. Blood pressure, heart rate, BMI measurements, WHR. Blood collection for zonulin and immunoglobulins against zonulin, calprotectin, CRP, HbA1c, HGB, RBC, WBC, PLT, creatinine, lipogram, ALT activity and oxidative stress parameters (SOD, GPx,CAT, GR, TOC, LPS, PSH, MDA, GSH, TAS (TAC).) . Postać leków to sposób, w jaki lek jest dostarczany do organizmu. Mogą to być tabletki, kapsułki, syropy, plastry, aerozole, maści itp. Wybór zależy od preferencji i potrzeb pacjenta. Postać leku wpływa na jego działanie, wchłanianie, metabolizm i wydalanie. In the case of antibiotic therapy, it is recommended to consume the supplement when you start taking the antibiotic and continue supplementation for 14 consecutive days after the end of antibiotic therapy. Sanprobi Barrier probiotic/placebo will be administrated and the gastrointestinal symptoms will be repeatedly assessed with the use of above mentioned questionnaire at certain time points during the study.

The investigators have chosen Sanprobi Barrier multi-strain formula probiotic because it is identical, in relation to bacterial strains and number, to Ecologic® BARRIER which has been proven in in vitro studies to improve the function of epithelial barrier of the intestine. It was also shown that 12-week administration of strains included in Ecologic® BARRIER in obese postmenopausal women improved intestinal barrier permeability marker (lipopolysaccharide) and cardiometabolic risk factors (waist, fat mass, subcutaneous fat, uric acid, total cholesterol, triglycerides, low-density lipoprotein cholesterol, glucose, insulin, and homeostatic model assessment - insulin resistance (HOMA-IR). The mechanism of the gastrointestinal intolerance in patients treated with metformin is poorly understood.The research was carried out at the Department of Dietetics and Clinical Nutrition (Medical University of Bialystok), Fitness Club Maniac Gym in Bialystok, as well as at the Hematological Diagnostics Department and the Biochemical Diagnostics Department of the University Teaching Hospital in Bialystok. Body composition analysis All competitors underwent body composition analysis using the InBody model 770 analyzer (South Korea). Bordalo Tonucci L, Dos Santos KM, De Luces Fortes Ferreira CL, Ribeiro SM, De Oliveira LL, Martino HS. Gut microbiota and probiotics: Focus on diabetes mellitus. Crit Rev Food Sci Nutr. 2017 Jul 24;57(11):2296-2309. doi: 10.1080/10408398.2014.934438. Store this product in the refrigerator, do not freeze. Heat or humidity may affect the live bacteria in this product, making it less effective.

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