Calprofen Ibuprofen Suspension Sachets, Sugar & Colour Free, Pain & Fever Relief for 3+ Months, Strawberry Flavour, 5 ml, 12-Count

Product Information

Cardiac glycosides: NSAIDs may exacerbate cardiac failure, reduce GFR and increased plasma cardiac glycoside levels. Ibuprofen should be used with caution in patients suffering from, or with a previous history of, bronchial asthma, chronic rhinitis or allergic disease, since such patients may have NSAID – sensitive asthma which has been associated with severe bronchospasm, urticaria or angioedema.

Ibuprofen is rapidly absorbed from the gastrointestinal tract, peak serum concentrations occurring 1–2 hours after administration. The elimination half-life is approximately 2 hours. Caution should be advised in patients receiving concomitant medications which could increase the risk of ulceration or bleeding, such as oral corticosteroids, anticoagulants such as warfarin, selective serotonin-reuptake inhibitors or anti-platelet agents such as aspirin (see section 4.5). Renal tubular acidosis and hypokalaemia have been reported in the post-marketing setting typically following prolonged use of the ibuprofen component at higher than recommended doses.Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors and the elderly. Discontinuation of NSAID therapy is usually followed by recovery to the pre-treatment state.

For infants aged 3 - 5 months medical advice should be sought if symptoms worsen or not later than 24 hours if symptoms persist.The concomitant consumption of excessive alcohol with NSAIDs, including ibuprofen, may increase the risk of adverse effects on the gastrointestinal tract, such as GI haemorrhage or the central nervous system possibly due to the additive effect. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. Most patients who have ingested clinically important amounts of NSAIDs will develop no more than nausea, vomiting, epigastric pain, or more rarely diarrhoea. Tinnitus, headache and gastrointestinal bleeding are also possible. In more serious poisoning, toxicity is seen in the central nervous system, manifesting as drowsiness, occasionally excitation and disorientation or coma. Occasionally patients develop convulsions. In serious poisoning metabolic acidosis may occur and the prothrombin time/INR may be prolonged, probably due to interference with the actions of circulating clotting factors. Acute renal failure and liver damage may occur.

Egton Medical Information Systems Limited. Registered in England and Wales. All rights reserved. Patient does not provide medical advice, diagnosis or treatment. Brufen is contraindicated in patients with severe heart failure (NYHA Class IV), hepatic failure and renal failure (see section 4.4). Anti-platelet agents and selective serotonin reuptake inhibitors (SSRIs) : Increased risk of gastrointestinal bleeding with NSAIDs (see section 4.4). Ibuprofen 100mg/5ml Oral Suspension should be given with care to patients with a history of heart failure or hypertension since oedema has been reported in association with ibuprofen administration.Give the missed dose as soon as you remember, unless it's nearly time for their next dose. In this case, skip the missed dose and give their next dose at the usual time.