Solgar Inositol 500 mg Vegetable Capsules - Vitamin B8 - Vegan, Vegetarian, Kosher, 50 Count (Pack of 1)

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Gregersen G, Bertelsen B, Harbo H, et al. Oral supplementation of myoinositol: effects on peripheral nerve function in human diabetics and on the concentration in plasma, erythrocytes, urine and muscle tissue in human diabetics and normals. Acta Neurol Scand 1983;67:164-72. View abstract. E., et al., Myo-inositol products in polycystic ovary syndrome (PCOS) treatment: quality, labeling accuracy, and cost comparison. Eur Rev Med Pharmacol Sci, 2011. 15(2): p. 165-74. V.R., et al., Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study. J Clin Endocrinol Metab, 2016. 101(4): p. 1754-61. Zarezadeh M, Dehghani A, Faghfouri AH, Radkhah N, Naemi Kermanshahi M, Hamedi Kalajahi F, Mohammadzadeh Honarvar N, Ghoreishi Z, Ostadrahimi A, Ebrahimi Mamaghani M Inositol supplementation and body mass index: A systematic review and meta-analysis of randomized clinical trials. Obes Sci Pract. (2022-Jun)

Susuki S et al. Urinary chiro-inositol excretion is an index marker of insulin sensitivity in Japanese type II diabetes. Diabetes Care. 1994 Dec;17(12):1465-8. Kiani AK, Paolacci S, Calogero AE, Cannarella R, Di Renzo GC, Gerli S, Della Morte C, Busetto GM, De Berardinis E, Del Giudice F, Stuppia L, Facchinetti F, Dinicola S, Bertelli M From Myo-inositol to D-chiro-inositol molecular pathways. Eur Rev Med Pharmacol Sci. (2021-Mar) For blood sugar control in type 2 diabetes: 1 gram of DCI and 400 mcg folic acid once daily for 6 months ( 34).Celentano C, Matarrelli B, Pavone G, et al. The influence of different inositol stereoisomers supplementation in pregnancy on maternal gestational diabetes mellitus and fetal outcomes in high-risk patients: a randomized controlled trial. J Matern Fetal Neonatal Med. 2020;33(5):743-751. View abstract. Bahadur A, Arora H, Ravi AK, et al. Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Cureus 2021;13(6):e15510. View abstract. Anxiety Symptoms - Gelber D, Levine J, Belmaker RH Effect of inositol on bulimia nervosa and binge eating Int J Eat Disord. (2001 Apr) In a prospective clinical study carried out in Rome in 2008, researchers investigated the effects of myo-inositol on two of the most common features of PCOS, hirsutism and hyperandrogenism. In the study, 46 women were evaluated at baseline and then again, following treatment with myo-inositol for 6 months. Results showed that treatment with myo-inositol significantly reduced hirsutism, hyperandrogenism and insulin resistance. 16

Weight - Gerli S, Papaleo E, Ferrari A, Di Renzo GC Randomized, double blind placebo-controlled trial: effects of myo-inositol on ovarian function and metabolic factors in women with PCOS Eur Rev Med Pharmacol Sci. (2007 Sep-Oct) Simonet BM, Ríos A, Grases F, Valcárcel M Determination of myo-inositol phosphates in food samples by flow injection-capillary zone electrophoresis. Electrophoresis. (2003-Jun)Phytic acid is the main source of dietary inositol. Some of the best high-inositol foods for women with PCOS include [ 7]: In a 2017 randomised controlled trial published in Gynecological Endocrinology, researchers compared the effects of metformin and myo-inositol on the clinical and metabolic features in PCOS. Fifty women with PCOS and either insulin resistance or hyperinsulinaemia were randomised to receive treatment with either metformin (1500 mg/day) or myo-inositol (4g / day). Results in both groups were similar: insulin sensitivity and BMI significantly improved in both groups, and the menstrual cycle was normalised in about 50% of the women. The researchers concluded that both metformin and myo-inositol have been demonstrated to be useful in women with PCOS for lowering BMI, improving insulin sensitivity, and improving menstrual cycle, without significant differences between the two treatments. 24 Donne, M., et al., Effects of three treatment modalities (diet, myoinositol or myoinositol associated with D-chiro-inositol) on clinical and body composition outcomes in women with polycystic ovary syndrome. Eur Rev Med Pharmacol Sci, 2019. 23(5): p. 2293-2301.