Solaray, Lithium Aspartate, 5 mg, 100 Capsules

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Lieu C.A., Dewey C.M., Chinta S.J., Rane A., Rajagopalan S., Batir S., Kim Y.H., Andersen J.K. Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model. Brain Res. 2014; 1591:111–117. [ PMC free article] [ PubMed] [ Google Scholar] Emotional or stress-eating is a real issue for many people, and by stabilizing mood, lithium orotate could prevent it from happening. While lithium is in your body, it affects neurotransmitters that are involved in the body’s stress reactions. The function of these neurotransmitters in stress reactions and lithium’s effects on them are outlined below.

In its purest form, lithium is a soft, light and silvery-white metal belonging to the alkali group on the periodic table. Knowing this, it may seem strange that the lithium salts lithium carbonate, lithium citrate and lithium sulfate, all inorganic substances, are often prescribed by psychiatrists for oral ingestion. So why exactly do professionals suggest eating metallic compounds to overcome psychiatric conditions, and what are the risks? Lithium in Your Body The therapy with Li has also been shown to increase density of the gray matter and increase the size of the amygdala and hippocampus. Li is also known to stimulate the production of neural stem cells and has protective effects against oxidative stress and its consequences [ 25, 35]. Do you have a specific question that this article didn’t answered? Send us a message and we’ll answer Goldstein MR, Mascitelli L (2016) Is violence in part a lithium deficiency state? Med Hypotheses 89:40–42 Lithium orotate has been researched as a treatment for alcoholism, and it showed promise since this addictive behavior is propelled by mood swings. Low-dose lithium could also be used to augment treatment for severe depression.

Foods high in lithium orotate

Jeon S.G., Yoo A., Chun D.W., Hong S.B., Chung H., Kim J.I., Moon M. The critical role of Nurr1 as a mediator and therapeutic target in Alzheimer's disease-related pathogenesis. Aging Dis. 2020; 11:705–724. [ PMC free article] [ PubMed] [ Google Scholar] Lithium orotate supplements are low-dose and therefore not an effective treatment for clinical depression. As it could help with a variety of different symptoms related to mood swings, it is expected to affect people with depression. Heghedus-Mindru G, Biron RK, Pejru DM, Rusnac LM, Rivis A, Stef DS (2008) Cation contents in natural mineral waters of Romania determined with the HPIC method. Food Agr Environ 6:506–508 I’ve used low-dose lithium for more than 15 years in my psychiatry practice, and it has consistently been one of the most helpful supplements for patients. I rarely see any side-effects, and patients typically report feeling less depressed and anxious and having fewer suicidal thoughts.

Mean disease duration for the low-dose, medium-dose and high-dose lithium-treated patients who received MRIs were 1.3 years, 1.5 years and 3.5 years, respectively. Correlations between the multi-shell FW values and those obtained using the MarkVCID script with only the b=1000 shell data exceeded 0.943 for all of the ROIs. There was an intra-class correlation coefficient of 0.94 between pSN FW data using MNI-defined and manual pSN ROI placement. It propelled Charles Leiper Grigg’s invention to become one of the bestselling beverages of all time. I’ve been taking this for years now. I don’t have mood swings or depression anymore, and my anxiety is a lot less.” Lithium Orotate Interactions Ayotte JD, Gronberg JM, Apodaca LE (2011) Trace elements and radon in groundwater across the United States, 1992–2003; Investigations Report; U.S. Geological Survey: Reston, VA, USAMost people get about 0.64-3 mg of lithium from food and water daily. This amount is extremely safe and has little to no side effects. Rat brain and serum lithium concentrations after acute injections of lithium carbonate and orotate” Journal of Pharmacy and Pharmacology (1978)

Harari F, Langeén M, Casimiro E, Bottai M, Palm B, Nordqvist H, Vahter M (2015) Environmental exposure to lithium during pregnancy and fetal size: a longitudinal study in the Argentinean Andes. Environ Int 77:48–54 Hoy A.R., Koay C.G., Kecskemeti S.R., Alexander A.L. Optimization of a free water elimination two-compartment model for diffusion tensor imaging. Neuroimage. 2014; 103:323–333. [ PMC free article] [ PubMed] [ Google Scholar] The risk of intentional abuse of the supplement or accidental poisoning due to interaction in the gastrointestinal tract or as a result of reduced Li of lithium from the body (low-sodium diet, renal failure) also constitutes an obstacle to increasing the intake of this element at a population level [ 46, 89]. Higher doses of Li could potentially lead to exacerbation of symptoms of some diseases, e.g., psoriasis in sensitive individuals [ 90]. It is also relevant to consider the possible side effects of low-dose Li on the functioning of the thyroid gland and kidneys, as well as on pregnancy and fetal development, although the risk of low-dose teratogenicity is considered to be relatively low [ 7, 74].Giotakos O, Nisianakis P, Tsouvelas G, Giakalou VV (2013) Lithium in the public water supply and suicide mortality in Greece. Biol Trace Elem Res:376–156, 379 Iglesias J.E., Insausti R., Lerma-Usabiaga G., Bocchetta M., Van Leemput K., Greve D.N., van der Kouwe A., Alzheimer's Disease Neuroimaging I., Fischl B., Caballero-Gaudes C., Paz-Alonso P.M. A probabilistic atlas of the human thalamic nuclei combining ex vivo MRI and histology. Neuroimage. 2018; 183:314–326. [ PMC free article] [ PubMed] [ Google Scholar] It is hypothesized that a very low Li intake can cause mood worsening and increase impulsiveness and nervousness [ 84]. This is partially supported by the increased frequency of suicide attempts, homicides, and acts of violence observed among populations within areas with low concentrations of Li in water resources (0–12 μg/L) [ 8, 57]. One of the hypotheses of the normothymic action of Li in the doses taken with the diet assumes that it may be required for the transport and absorption of vitamin B12 and folates that are involved in neuromodulation and the normal course of biochemical transformations in the central nervous system. Thus, limited intake of Li could also inhibit action of these compounds [ 17, 23]. The levels of Li in water and in food, and therefore its daily intake in some parts of the world, are low: below the provisional recommendation established by Schrauzer (2002) at 1000 μg [ 11, 58]. It was therefore suggested that in individuals inhabiting such regions, Li supplementation could be considered [ 23]. This would be possible either by using food supplements containing lower than therapeutic doses of Li or by introducing additional products enriched in this element, just as salt is commonly enriched with iodine.